Problems in the hematological diagnosis of unusual coagulation disorders

ABSTRACT

Thirteen cases of severe coagulation disorders occuring during the past 5 years and investigated at the Government Pathological Laboratory, Jamaica are discussed. Nine of these were hemophilias, one had Christmas disease and three further cases which presented complicated aberrations are discussed in detail. Of this latter group one had multiple congenital deficiency of prothrombin complex (i.e. prothrombin factor VII and factor X) and the other two, who were siblings, had multiple anomalies (anti-hemophilic globulin deficiency, a circulating anti-coagulant acting as a thrombo-plastin inhibitor as well as a plasma thromboplastin antecedent deficiency) (AU)