Caracterizacion antigenica e inmunogenica de varias cepas del serotipo Indiana de estomatitis vesicular aisladas en Brasil / Antigenic and immunogenic characterization of various strains of the Indiana serotype of vesicular stomatitis isolated in Brazil

ABSTRACT

Antigenic studies performed with vesicular stomatitis (VS) virus strains of the serotype Indiana (IND), Rancharia-Brazil/66 and Riberao-Brazil/78, isolated in the state of Sao Paulo, Brazil in 1966 and 1979, respectively, indicated that they have to be classified within the subtype IND-2 and that they are related to virus strains Salto-Argentina/63 and Cocal-Trinidad/61. The Espinoza-Brazil/77 strain isolated in 1977 in cattle of the state of Minas Gerais is closely related to the Alagoas-Brazil/64 strain, subtype IND-3. Studies of sera from recovered animals and immunodiffusion gel agar test confirmed the results obtained by 50 percent complement fixation tests. Field pathogenicity indicated that strains from the subtype IND-2 only affected horses, while the IND-3 subtype viruses affected cattle to a lower degree in comparison with horses. The northeast states and Minas Gerais, in Brazil, are affected by VS virus subtype IND-3, while in Sao Paulo and Rio Grande do Sul subtype IND-2 strains are identified