Estudios sobre la infeccion de ratones endogamicos con clones de Trypanosoma cruzi / Infection of inbred mice with Trypanosoma cruzi clones
Boletín de la Oficina Sanitaria Panamericana (OSP)
; 103(2),ago. 1987 ilus
Article
| PAHO-IRIS
| ID: phr-18014
Responsible library:
US1.1
ABSTRACT
The project, which is ongoing, consists of infecting strains of inbred mice with stocks of single-cell-isolated clones of Trypanosoma cruzi and studying the course and outcome of these infections. Research procedures included the determination of the following aspects 1) virulence spectrum of T. cruzi clones; 2) mouse strain-dependent susceptibility to infection with T. cruzi clones; 3) effect of the number of parasites inoculated on the outcome of infection with T. cruzi clones; 4) influence of the route of inoculation on the outcome of infection; 5) influence of the handling of the parasite on the outcome of infection; 6) influence of the infection by one T. cruzi clone upon the outcome of infection by a second clone, and 7) a multiparametric, time series analysis of the course of infection in a large group of mice for the development of a chronic Chagas' disease model
Full text:
Available
Collection:
Databases of international organizations
Health context:
Neglected Diseases
Health problem:
Chagas Disease
/
Neglected Diseases
Database:
PAHO-IRIS
Main subject:
Trypanosoma cruzi
/
Chagas Disease
/
Disease Models, Animal
/
Disease Susceptibility
Year:
1987
Document type:
Article