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Antiviral activity of plant juices and green tea against SARS-CoV-2 and influenza virus in vitro
Bruno Frank; Carina Conzelmann; Tatjana Weil; Ruediger Gross; Peggy Jungke; Maren Eggers; Janis A Mueller; Jan Muench; Uwe Kessler.
Affiliation
  • Bruno Frank; CogniVerde GmbH
  • Carina Conzelmann; Institute of Molecular Virology, Ulm University Medical Center
  • Tatjana Weil; Institute of Molecular Virology, Ulm University Medical Center
  • Ruediger Gross; Institute of Molecular Virology, Ulm University Medical Center
  • Peggy Jungke; Technische Universitaet Dresden
  • Maren Eggers; Labor Prof. Dr. G. Enders MVZ GbR
  • Janis A Mueller; Institute of Molecular Virology, Ulm University Medical Center
  • Jan Muench; Institute of Molecular Virology, Ulm University Medical Center
  • Uwe Kessler; CogniVerde GmbH
Preprint in English | bioRxiv | ID: ppbiorxiv-360545
ABSTRACT
Many plant juices, extracts and teas have been shown to possess antiviral activity. We here analyzed the virucidal activity of black chokeberry (Aronia melanocarpa), pomegranate (Punica granatum), and elderberry (Sambucus nigra) juice, as well as green tea (Camellia sinensis) against different respiratory viruses. We found that all tested plant derived products effectively inactivated influenza virus, whereas only chokeberry juice diminished SARS-CoV-2 and vaccinia virus infectivity. None of the products inactivated non-enveloped human adenovirus type 5. Thus, black chokeberry juice exerts virucidal activity against different enveloped viral pathogens under in vitro conditions. Whether application of virucidal juices or green tea as oral rinses may lower viral loads in the oral cavity in vivo remains to be evaluated.
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Full text: Available Collection: Preprints Database: bioRxiv Type of study: Experimental_studies Language: English Year: 2020 Document type: Preprint
Full text: Available Collection: Preprints Database: bioRxiv Type of study: Experimental_studies Language: English Year: 2020 Document type: Preprint
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