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Experimental SARS-CoV-2 infection of bank voles - general susceptibility but lack of direct transmission
Lorenz Ulrich; Anna Michelitsch; Nico Halwe; Kerstin Wernike; Donata Hoffmann; Martin Beer.
Affiliation
  • Lorenz Ulrich; Friedrich-Loeffler-Institut
  • Anna Michelitsch; Friedrich-Loeffler-Institut
  • Nico Halwe; Friedrich-Loeffler-Institut
  • Kerstin Wernike; Friedrich-Loeffler-Institut
  • Donata Hoffmann; Friedrich-Loeffler-Institut
  • Martin Beer; Friedrich-Loeffler-Institut
Preprint in English | bioRxiv | ID: ppbiorxiv-424203
ABSTRACT
After experimental inoculation, SARS-CoV-2 infection was proven for bank voles by seroconversion within eight days and detection of viral RNA in nasal tissue for up to 21 days. However, transmission to contact animals was not detected. Therefore, bank voles are unlikely to establish effective SARS-CoV-2 transmission cycles in nature. Article Summary LineBank voles show low-level viral replication and seroconversion upon infection with SARS-CoV-2, but lack transmission to contact animals.
License
cc_by_nc_nd
Full text: Available Collection: Preprints Database: bioRxiv Language: English Year: 2020 Document type: Preprint
Full text: Available Collection: Preprints Database: bioRxiv Language: English Year: 2020 Document type: Preprint
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