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SARS-CoV-2 infection in domestic rats after transmission from their infected owner
Xavier Montagutelli; Berenice Decaudin; Maxime Beretta; Hugo Mouquet; Etienne Simon-Loriere.
Affiliation
  • Xavier Montagutelli; Institut Pasteur, Universite Paris Cite, Mouse Genetics Laboratory, Paris, France
  • Berenice Decaudin; Service NAC, Centre Hospitalier Veterinaire Advetia, Velizy-Villacoublay, France
  • Maxime Beretta; Institut Pasteur, Universite Paris Cite, Laboratory of Humoral Immunology, Paris, France
  • Hugo Mouquet; Institut Pasteur, Universite Paris Cite, Laboratory of Humoral Immunology, Paris, France
  • Etienne Simon-Loriere; Institut Pasteur, Universite Paris Cite, G5 Evolutionary Genomics of RNA Viruses, Paris, France
Preprint in English | bioRxiv | ID: ppbiorxiv-512053
ABSTRACT
We report the transmission of SARS-CoV-2 Omicron variant from a COVID-19 symptomatic individual to two domestic rats, one of which developed severe symptoms. Omicron carries several mutations which permit rodent infection. This report demonstrates that pet, and likely wild, rodents could therefore contribute to SARS-CoV-2 spread and evolution.
License
cc_by_nc_nd
Full text: Available Collection: Preprints Database: bioRxiv Language: English Year: 2022 Document type: Preprint
Full text: Available Collection: Preprints Database: bioRxiv Language: English Year: 2022 Document type: Preprint
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