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Clinical outcomes of 402 patients with COVID-2019 from a single center in Wuhan, China
Yingjie Wu; Wei Guo; Huan Liu; Bei Qi; Ke Liang; Bo Xu; Zhiyong Peng; Shu-Yuan Xiao.
Affiliation
  • Yingjie Wu; Zhongnan Hospital of Wuhan University
  • Wei Guo; Zhongnan Hospital of Wuhan University
  • Huan Liu; Zhongnan Hospital of Wuhan University
  • Bei Qi; Zhongnan Hospital of Wuhan University
  • Ke Liang; Zhongnan Hospital of Wuhan University
  • Bo Xu; Zhongnan Hospital of Wuhan University
  • Zhiyong Peng; Zhongnan Hospital of Wuhan University
  • Shu-Yuan Xiao; Zhongnan Hospital of Wuhan University
Preprint in English | medRxiv | ID: ppmedrxiv-20032672
ABSTRACT
The SARS-CoV-2 outbreak is causing widespread infections and significant mortality. Previous studies describing clinical characteristics of the disease contained small cohorts from individual centers or larger series consisting of mixed cases from different hospitals. We report analyses of mortality and disease severity among 402 patients from a single hospital. The cohort included 297 patients with confirmed and 105 with suspected diagnosis. The latter group met the criteria for clinical diagnosis but nucleic acid tests results were initially interpreted as suspicious. Data were compared between genders and among different age groups. The overall case fatality is 5.2%. However, patients 70 years of age or older suffered a significantly higher mortality (17.8%), associated with more patients having severe or critical illness (57.5%). Patients 50 years of age or older had a mortality of 8.0%, and those younger than 50 years, 1.2%. Male patients had a mortality of 7.6% versus 2.9% in females.
License
cc_by_nc_nd
Full text: Available Collection: Preprints Database: medRxiv Type of study: Cohort_studies / Experimental_studies / Observational study / Prognostic study / Rct Language: English Year: 2020 Document type: Preprint
Full text: Available Collection: Preprints Database: medRxiv Type of study: Cohort_studies / Experimental_studies / Observational study / Prognostic study / Rct Language: English Year: 2020 Document type: Preprint
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