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Estimation of protection for COVID-19 in children from epidemiological information and estimate effect of policy in Japan
Junko Kurita; Yoshiyuki Sugishita; Tamie Sugawara; Yasushi Ohkusa.
Affiliation
  • Junko Kurita; Center for Medical Sciences, Ibaraki Prefectural University of Health Sciences, Ibaraki, Japan
  • Yoshiyuki Sugishita; National Institute of Infectious Diseases, Tokyo, Japan
  • Tamie Sugawara; National Institute of Infectious Diseases, Tokyo, Japan
  • Yasushi Ohkusa; National Institute of Infectious Diseases, Tokyo, Japan
Preprint in English | medRxiv | ID: ppmedrxiv-20045252
ABSTRACT
BackgroundIncidence in children was much less than in adults during the COVID-19 outbreak. Sports and entertainment events were canceled (VEC) in Japan for two weeks during 26 February - 13 March. Most schools were closed (SC). ObjectWe construct a susceptible-infected-recovered model using three age classes and estimate the basic reproduction number (R0) and protection level among children simultaneously. Then we simulate SC and VEC effects. MethodWe used data of patients with symptoms in Japan during 14 January to assess SC and VEC introduction. Effects of SC and VEC were incorporated into the model through change in the contact pattern or frequencies among age classes. ResultsResults suggest R0 as 2.86 [95%CI of 2.73, 2.97]. The protection level was estimated as 0.4 [0.2, 0.7]. SC and VEC can reduce the total number of patients significantly, by 6-7%. Discussion and ConclusionThe estimated R0 was similar to that found from other studies in China and Japan. We found a significant protection level among children, and by effects of SC and VEC.

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Full text: Available Collection: Preprints Database: medRxiv Type of study: Experimental_studies / Observational study Language: English Year: 2020 Document type: Preprint
Full text: Available Collection: Preprints Database: medRxiv Type of study: Experimental_studies / Observational study Language: English Year: 2020 Document type: Preprint
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