This article is a Preprint
Preprints are preliminary research reports that have not been certified by peer review. They should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.
Preprints posted online allow authors to receive rapid feedback and the entire scientific community can appraise the work for themselves and respond appropriately. Those comments are posted alongside the preprints for anyone to read them and serve as a post publication assessment.
Observer agreement and clinical significance of chest CT reporting in patients suspected of COVID-19
Preprint
in En
| PREPRINT-MEDRXIV
| ID: ppmedrxiv-20094102
Journal article
A scientific journal published article is available and is probably based on this preprint. It has been identified through a machine matching algorithm, human confirmation is still pending.
See journal article
A scientific journal published article is available and is probably based on this preprint. It has been identified through a machine matching algorithm, human confirmation is still pending.
See journal article
ABSTRACT
ObjectivesTo assess inter-observer agreement and clinical significance of chest CT reporting in patients suspected of COVID-19. MethodsFrom 16th to 24th March 2020, 241 consecutive patients addressed to hospital for COVID-19 suspicion had both chest CT and SARS-CoV-2 RT-PCR. Eight observers (2 thoracic and 2 general senior radiologists, 2 junior radiologists and 2 emergency physicians) retrospectively categorized each CT into one out of 3 categories (evocative, compatible for COVID-19 pneumonia, and not evocative or normal). Observer agreement for categorization between all readers and pairs of readers with similar experience was evaluated with the Kappa coefficient. The results of a consensus categorization were correlated to RT-PCR. ResultsObserver agreement across the 3 categories was good between all readers ({kappa} value 0.68 95%CI 0.67-0.70) and good to very good between pairs of readers (0.64-0.85). It was very good ({kappa} 0.81 95%CI 0.79-0.83), fair ({kappa} 0.32 95%CI 0.29-0.34) and good ({kappa} 0.74 95%CI 0.71-0.76) for the categories evocative, compatible and not evocative or normal, respectively. RT-PCR was positive in 97%, 50% and 27% of cases classified in the respective categories. Observer agreement was lower (p=0.045) and RT-PCR positive cases were less frequently categorized evocative in presence of an underlying pulmonary disease (p<0.001). ConclusionInter-observer agreement for chest CT reporting using categorization of findings is good in patients suspected of COVID-19. Among patients considered for hospitalization in an epidemic context, CT categorized evocative is highly predictive of COVID-19, whereas the predictive value of CT decreases between the categories compatible and not evocative. Key resultsO_LIInter-observer agreement for chest CT reporting into categories is good in patients suspected of COVID-19 C_LIO_LIChest CT can participate in estimating the likelihood of COVID-19 in patients presenting to hospital during the outbreak, CT categorized <
cc_no
Full text:
1
Collection:
09-preprints
Database:
PREPRINT-MEDRXIV
Type of study:
Experimental_studies
/
Prognostic_studies
Language:
En
Year:
2020
Document type:
Preprint