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Reproducing SARS-CoV-2 epidemics byregion-specific variables and modeling contacttracing App containment
Alberto Ferrari; Enrico Santus; Davide Cirillo; Miguel Ponce-de-Leon; Nicola Marino; Maria Teresa Ferretti; Antonella Santuccione Chadha; Nikolaos Mavridis; Alfonso Valencia.
Affiliation
  • Alberto Ferrari; FROM research foundation
  • Enrico Santus; Bayer, Decision Science & Advanced Analytics for MA, PV & RA Division.
  • Davide Cirillo; Barcelona Supercomputing Center (BSC), C/ Jordi Girona 29, 08034, Barcelona,Spain.
  • Miguel Ponce-de-Leon; Barcelona Supercomputing Center (BSC), C/ Jordi Girona 29, 08034, Barcelona,Spain.
  • Nicola Marino; Women's Brain Project (WBP), Gunterhausen, Switzerland
  • Maria Teresa Ferretti; Women's Brain Project (WBP), Gunterhausen, Switzerland
  • Antonella Santuccione Chadha; Women's Brain Project (WBP), Gunterhausen, Switzerland
  • Nikolaos Mavridis; Interactive Robots and Media Laboratory (IRLM), United Arab Emirates.
  • Alfonso Valencia; Barcelona Supercomputing Center (BSC), C/ Jordi Girona 29, 08034, Barcelona,Spain.
Preprint in English | medRxiv | ID: ppmedrxiv-20101675
Journal article
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ABSTRACT
Targeted contact-tracing through mobile phone apps has been proposed as an instrument to help contain the spread of COVID-19 and manage the lifting of nation-wide lockdowns currently in place in USA and Europe. However, there is an ongoing debate on its potential efficacy, especially in the light of region-specific demographics. We built an expanded SIR model of COVID-19 epidemics that accounts for region-specific population densities, and we used it to test the impact of a contact-tracing app in a number of scenarios. Using demographic and mobility data from Italy and Spain, we used the model to simulate scenarios that vary in baseline contact rates, population densities and fraction of app users in the population. Our results show that, in support of efficient isolation of symptomatic cases, app-mediated contact-tracing can successfully mitigate the epidemic even with a relatively small fraction of users, and even suppress altogether with a larger fraction of users. However, when regional differences in population density are taken into consideration, the epidemic can be significantly harder to contain in higher density areas, highlighting potential limitations of this intervention in specific contexts. This work corroborates previous results in favor of app-mediated contact-tracing as mitigation measure for COVID-19, and draws attention on the importance of region-specific demographic and mobility factors to achieve maximum efficacy in containment policies.
License
cc_by_nc_nd
Full text: Available Collection: Preprints Database: medRxiv Language: English Year: 2020 Document type: Preprint
Full text: Available Collection: Preprints Database: medRxiv Language: English Year: 2020 Document type: Preprint
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