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Anti-SARS-CoV-2 IgG antibodies are associated with reduced viral load
Andrew Bryan; Susan L Fink; Meghan A Gattuso; Gregory Pepper; Anu Chaudhary; Mark Wener; Chihiro Morishima; Keith Jerome; Patrick C Mathias; Alexander L Greninger.
Affiliation
  • Andrew Bryan; University of Washington School of Medicine
  • Susan L Fink; University of Washington School of Medicine
  • Meghan A Gattuso; Aquaelis
  • Gregory Pepper; University of Washington
  • Anu Chaudhary; University of Washington School of Medicine
  • Mark Wener; University of Washington School of Medicine
  • Chihiro Morishima; University of Washington School of Medicine
  • Keith Jerome; University of Washington School of Medicine
  • Patrick C Mathias; University of Washington School of Medicine
  • Alexander L Greninger; University of Washington
Preprint in English | medRxiv | ID: ppmedrxiv-20110551
ABSTRACT
Anti-SARS-CoV-2 antibodies have been described, but correlation with virologic outcomes is limited. Here, we find anti-SARS-CoV-2 IgG to be associated with reduced viral load. High viral loads were rare in individuals who had seroconverted. Higher viral load on admission was associated with increased 30-day mortality (OR 4.20 [95% CI 1.62-10.86]).
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Full text: Available Collection: Preprints Database: medRxiv Language: English Year: 2020 Document type: Preprint
Full text: Available Collection: Preprints Database: medRxiv Language: English Year: 2020 Document type: Preprint
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