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COVID-19 trend in Bangladesh: deviation from epidemiological model and critical analysis of the possible factors
Preprint
in English
| medRxiv
| ID: ppmedrxiv-20118745
ABSTRACT
BackgroundSince its first report on March 08, COVID-19 positive cases and number of deaths are increasing in Bangladesh. In the first month of COVID-19 infection, incidence of daily positive cases did follow the susceptible, infected and recovered (SIR) based predictions we reported in April, but started to deviate in the following months. COVID-19 transmission and disease progression depends on multifaceted determinants e.g. viral genetics, host immunity, social distancing, co-morbidity, socio-demographic and environmental parameters. Therefore deviation in confirmed cases from predicted model may appear and warrant thorough investigation. MethodsIn this short report, we compared real data with SIR model and analyzed the possible factors associated with the deviation which included preventive intervention strategies, socioeconomic capabilities, climatic and meteorological indexes, acquired immunity of Bangladeshi population, demographic characteristics, health indicators and food habits. ResultsThe key factor responsible for the observed deviation was found to be the number of tests performed. Having population with low median age, young age groups are being mostly infected. Low prevalence of non-communicable diseases among them and strong immunity compared to the elderly might have kept most of them asymptomatic with silent recovery. Warm temperature, humidity and UV index of Bangladesh during this summer period might have contributed to the slow progression of infection. Longer daylight mediated immunity, fresh air circulations and ventilation, less population density in rural areas and certain food habits perhaps helped the large number of populations to restrict the infection up to a level. ConclusionDespite all these helpful determinants in Bangladesh, person to person contact is still the leading risk factor for COVID-19 transmission. Infection may increase rapidly if safe distance and preventive measures are not strictly followed while resuming the normal social and work life. Expanding test capacity, strong collaborative action plans, strategies and implementation are needed immediately to prevent catastrophe. HighlightsO_LILimited number of tests compared to large population was the key reason for possible low daily positive cases reported in Bangladesh. C_LIO_LIControlled interventions viz. official leave; transport ban and social distancing had helped initially to slow down the transmission. C_LIO_LIWarm weather, high humidity and UV index, sunlight mediated immunity, fresh air circulations, low pollutions, food habit and heterologous immunity might have reduced the transmission capabilities of SARS-CoV-2. C_LIO_LIHaving large number of young people with strong immunity might have kept most of the infected asymptomatic who recovered silently. C_LIO_LIPerson to person contact still remain as key risk factor in COVID-19 transmission, so strict health measures should be in place even after reopening social activities to contain further transmission. C_LI
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Collection:
Preprints
Database:
medRxiv
Type of study:
Experimental_studies
/
Observational study
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Prognostic study
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Rct
Language:
English
Year:
2020
Document type:
Preprint