Evolution and impact of COVID-19 outbreaks in care homes: population analysis in 189 care homes in one geographic region

ABSTRACT

BackgroundCOVID-19 has had large impact on care-home residents internationally. This study systematically examines care-home outbreaks of COVID-19 in a large Scottish health board. MethodsAnalysis of testing, cases and deaths using linked care-home, testing and mortality data for 189 care-homes with 5843 beds in a large Scottish Health Board up to 15/06/20. Findings70 (37.0%) of care-homes experienced a COVID-19 outbreak, 66 of which were in care-homes for older people where care-home size was strongly associated with outbreaks (OR per 20-bed increase 3.50, 95%CI 2.06 to 5.94). There were 852 confirmed cases and 419 COVID-related deaths, 401 (95.7%) of which occurred in care-homes with an outbreak, 16 (3.8%) in hospital, and two in the 119 care-homes without a known outbreak. For non-COVID related deaths, there were 73 excess deaths in care-homes with an outbreak, but no excess deaths in care-homes without an outbreak, and 24 fewer deaths than expected of care-home residents in hospital. A quarter of COVID-19 related cases and deaths occurred in five (2.6%) care-homes, and half in 13 (6.9%) care-homes. InterpretationThe large impact on excess deaths appears to be primarily a direct effect of COVID-19, with cases and deaths are concentrated in a minority of care homes. A key implication is that there is a large pool of susceptible residents if community COVID-19 incidence increases again. Shielding residents from potential sources of infection and rapid action into minimise outbreak size where infection is introduced will be critical in any wave 2. FundingNot externally funded. O_TEXTBOXResearch in context Evidence before this study We searched PubMed and the medRxiv preprint server using terms long-term care, nursing home, care home, or residential care combined with COVID-19 and/or SARS-CoV-2, updated to 25th June. The existing published literature highlights the large impact in care-homes, and that atypical disease presentation, asymptomatic carriage and a presymptomatic infectious period is common in both residents and staff. One living systematic review confirms the international outbreak burden among residents and staff and high but varied international mortality rates. International modelling studies have failed to take account of the care-home environment and context, making estimates informed by general community transmission of infection. Only one peer-reviewed study was identified which evaluated US nursing home characteristics associated with outbreaks, finding associations with larger facility size, urban location, and ethnicity, but no association with quality ratings or ownership. Added value of this study This study reports data for all 189 care homes in one large Scottish health board, where 37% experienced an outbreak of COVID-19, with 95% of outbreaks in care-homes for older people. The number of beds was the only care-home characteristic statistically significantly associated with the presence of an outbreak. One-third of affected care homes had only single cases or short outbreaks, but sustained outbreaks were common, and there was evidence of potential reintroduction of infection in some care-homes with >14 day gaps between confirmed cases. Cases and mortality were heavily concentrated. In care-homes with an outbreak there were 472 excess deaths (12.3% of bed capacity, 3.1 times the average in the previous five years), 85% of which were COVID-19 related. There were only 16 COVID-19 related deaths and 14 other deaths of care-home residents in hospital in the same period, consistent with [~]20 non-COVID excess deaths occurring in care-homes being deaths that would have happened anyway. 99% of the excess deaths and of the COVID-19 related deaths were in care-homes with an outbreak, suggesting that quality and safety of care in the wider care system was not affected. Implications of all the available evidence Outbreak patterns varied considerably and more detailed understanding of why some care homes avoided or controlled outbreaks would allow learning to prepare for wave two. Systematic, regular testing and use of whole genome sequencing will inform understanding of transmission dynamics and future outbreak management. Future research should consider the built environment and organisation of care as other potentially modifiable factors to support infection control. Improving national and local data on the care-home population is a priority both for COVID-19 and for ensuring this vulnerable population receives better care in the future. C_TEXTBOX