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Kinetics of SARS-CoV-2 Antibody Avidity Maturation and Association with Disease Severity
Yiqi Ruben Luo; Indrani Chakraborty; Cassandra Yun; Alan H.B. Wu; Kara Lake Lynch.
Affiliation
  • Yiqi Ruben Luo; University of California San Francisco
  • Indrani Chakraborty; Gator Bio
  • Cassandra Yun; University of California San Francisco
  • Alan H.B. Wu; University of California San Francisco
  • Kara Lake Lynch; University of California San Francisco
Preprint in English | medRxiv | ID: ppmedrxiv-20165522
ABSTRACT
The kinetics of IgG avidity maturation during SARS-CoV-2 infection was studied. The IgG avidity assay used a novel label-free immunoassay technology. It was found that there was a strong correlation between IgG avidity and days since symptom onset, and peak readings were significantly higher in severe than mild disease cases.
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Full text: Available Collection: Preprints Database: medRxiv Type of study: Prognostic study Language: English Year: 2020 Document type: Preprint
Full text: Available Collection: Preprints Database: medRxiv Type of study: Prognostic study Language: English Year: 2020 Document type: Preprint
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