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The effectiveness of population-wide, rapid antigen test based screening in reducing SARS-CoV-2 infection prevalence in Slovakia
Martin Pavelka; Kevin van Zandvoort; Sam Abbott; Katharine Sherratt; Marek Majdan; - CMMID COVID-19 working group; - Institut Zdravotnych Analyz; Pavel Jarcuska; Marek Krajci; Stefan Flasche; Sebastian Funk.
Affiliation
  • Martin Pavelka; Slovak Ministry of Health
  • Kevin van Zandvoort; London School of Hygiene & Tropical Medicine
  • Sam Abbott; London School of Hygiene & Tropical Medicine
  • Katharine Sherratt; London School of Hygiene & Tropical Medicine
  • Marek Majdan; Trnava University
  • - CMMID COVID-19 working group; -
  • - Institut Zdravotnych Analyz; -
  • Pavel Jarcuska; Pavol Jozef Safarik University
  • Marek Krajci; Slovak Ministry of Health
  • Stefan Flasche; London School of Hygiene & Tropical Medicine
  • Sebastian Funk; London School of Hygiene & Tropical Medicine
Preprint in English | medRxiv | ID: ppmedrxiv-20240648
ABSTRACT
Slovakia conducted multiple rounds of population-wide rapid antigen testing for SARS-CoV-2 in late 2020, combined with a period of additional contact restrictions. Observed prevalence decreased by 58% (95% CI 57-58%) within one week in the 45 counties that were subject to two rounds of mass testing, an estimate that remained robust when adjusting for multiple potential confounders. Adjusting for epidemic growth of 4.4% (1.1-6.9%) per day preceding the mass testing campaign, the estimated decrease in prevalence compared to a scenario of unmitigated growth was 70% (67-73%). Modelling suggests that this decrease cannot be explained solely by infection control measures, but requires the additional impact of isolation as well as quarantine of household members of those testing positive.
License
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Full text: Available Collection: Preprints Database: medRxiv Type of study: Experimental_studies / Observational study Language: English Year: 2020 Document type: Preprint
Full text: Available Collection: Preprints Database: medRxiv Type of study: Experimental_studies / Observational study Language: English Year: 2020 Document type: Preprint
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