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Non-pharmaceutical interventions and inoculation rate shape SARS-COV-2 vaccination campaign success
Marta Galanti; Sen Pei; Teresa K Yamana; Frederick J Angulo; Apostolos Charos; Farid Khan; Kimberly Shea; David Swerdlow; Jeffrey Shaman.
Affiliation
  • Marta Galanti; Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University
  • Sen Pei; Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University
  • Teresa K Yamana; Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University
  • Frederick J Angulo; Medical Development and Scientific/Clinical Affairs, Pfizer Vaccines
  • Apostolos Charos; Patient and Health Impact, Pfizer Vaccines
  • Farid Khan; Medical Development and Scientific/Clinical Affairs, Pfizer Vaccines
  • Kimberly Shea; Patient and Health Impact, Pfizer Vaccines
  • David Swerdlow; Medical Development and Scientific/Clinical Affairs, Pfizer Vaccines
  • Jeffrey Shaman; Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University
Preprint in En | PREPRINT-MEDRXIV | ID: ppmedrxiv-21252240
ABSTRACT
Nearly one year into the COVID-19 pandemic, the first SARS-COV-2 vaccines received emergency use authorization and vaccination campaigns began. A number of factors can reduce the averted burden of cases and deaths due to vaccination. Here, we use a dynamic model, parametrized with Bayesian inference methods, to assess the effects of non-pharmaceutical interventions, and vaccine administration and uptake rates on infections and deaths averted in the United States. We estimate that high compliance with non-pharmaceutical interventions could avert more than 60% of infections and 70% of deaths during the period of vaccine administration, and that increasing the vaccination rate from 5 to 11 million people per week could increase the averted burden by more than one third. These findings underscore the importance of maintaining non-pharmaceutical interventions and increasing vaccine administration rates.
License
cc_by_nc
Full text: 1 Collection: 09-preprints Database: PREPRINT-MEDRXIV Type of study: Experimental_studies Language: En Year: 2021 Document type: Preprint
Full text: 1 Collection: 09-preprints Database: PREPRINT-MEDRXIV Type of study: Experimental_studies Language: En Year: 2021 Document type: Preprint