Background rates of all-cause mortality, hospitalizations, and emergency department visits among nursing home residents in Ontario, Canada to inform COVID-19 vaccine safety assessments

Maria Sundaram; Sharifa Nasreen; Andrew Calzavara; Siyi He; Hannah Chung; Susan E Bronskill; Sarah A Buchan; Mina Tadrous; Peter Tanuseputro; Kumanan Wilson; Sarah Wilson; Jeff Kwong; - Canadian Immunization Research Network (CIRN) Investigators

This article is a Preprint

Preprints are preliminary research reports that have not been certified by peer review. They should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

Preprints posted online allow authors to receive rapid feedback and the entire scientific community can appraise the work for themselves and respond appropriately. Those comments are posted alongside the preprints for anyone to read them and serve as a post publication assessment.

Background rates of all-cause mortality, hospitalizations, and emergency department visits among nursing home residents in Ontario, Canada to inform COVID-19 vaccine safety assessments

Maria Sundaram; Sharifa Nasreen; Andrew Calzavara; Siyi He; Hannah Chung; Susan E Bronskill; Sarah A Buchan; Mina Tadrous; Peter Tanuseputro; Kumanan Wilson; Sarah Wilson; Jeff Kwong; - Canadian Immunization Research Network (CIRN) Investigators.

Affiliation

Maria Sundaram; ICES; Dalla Lana School of Public Health, University of Toronto
Sharifa Nasreen; Dalla Lana School of Public Health, University of Toronto
Andrew Calzavara; ICES
Siyi He; ICES
Hannah Chung; ICES
Susan E Bronskill; ICES; Dalla Lana School of Public Health, University of Toronto; Women's College Research Institute, Toronto
Sarah A Buchan; Public Health Ontario
Mina Tadrous; ICES; Public Health Ontario
Peter Tanuseputro; ICES; Department of Medicine, University of Ottawa and Bruyere and Ottawa Hospital Research Institutes, Ottawa
Kumanan Wilson; Department of Medicine, University of Ottawa and Bruyere and Ottawa Hospital Research Institutes, Ottawa
Sarah Wilson; ICES; Dalla Lana School of Public Health, University of Toronto; Public Health Ontario
Jeff Kwong; ICES
- Canadian Immunization Research Network (CIRN) Investigators;

Preprint in En | PREPRINT-MEDRXIV | ID: ppmedrxiv-21253290

Journal article
A scientific journal published article is available and is probably based on this preprint. It has been identified through a machine matching algorithm, human confirmation is still pending.
See journal article

ABSTRACT

ABSTRACT

BackgroundNursing home (NH) residents are prioritized for COVID-19 vaccination. We report monthly mortality, hospitalizations, and emergency department (ED) visit incidence rates (IRs) during 2010-2020 to provide context for COVID-19 vaccine safety assessments. MethodsWe observed outcomes among NH residents using administrative databases. IRs were calculated by month, sex, and age group. Comparisons between months were assessed using one-sample t-tests; comparisons by age and sex were assessed using chi-squared tests. ResultsFrom 2010-2019, there were 83,453 (SD 652.4) NH residents per month, with an average of 2.3 (SD 0.28) deaths, 3.1 (SD 0.16) hospitalizations, and 3.6 (SD 0.17) ED visits per 100 residents per month. From March to December 2020, mortality IRs were increased, but hospitalization and ED visit IRs were reduced (p<0.05). ConclusionWe identified consistent monthly mortality, hospitalization, and ED visit IRs during 2010-2019. Marked differences in these rates were observed during 2020, coinciding with the COVID-19 pandemic.

License

cc_no

Fulltext

Add to My VHL

XML

Search on Google

Full text: 1 Collection: 09-preprints Database: PREPRINT-MEDRXIV Type of study: Observational_studies Language: En Year: 2021 Document type: Preprint

Fulltext

Add to My VHL

XML

Search on Google

Full text: 1 Collection: 09-preprints Database: PREPRINT-MEDRXIV Type of study: Observational_studies Language: En Year: 2021 Document type: Preprint