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Severity, criticality, and fatality of the SARS-CoV-2 Beta variant
Laith J Abu-Raddad; Hiam Chemaitelly; Houssein H. Ayoub; HADI M. YASSINE; Fatiha Benslimane; Hebah A. Al Khatib; Patrick Tang; Mohammad Rubayet Hasan; Peter Coyle; Sawsan AlMukdad; Zaina Al Kanaani; Einas Al Kuwari; Andrew Jeremijenko; Anvar Hassan Kaleeckal; Ali Nizar Latif; Riyazuddin Mohammad Shaik; Hanan F. Abdul Rahim; Gheyath Nasrallah; Mohamed Ghaith Al Kuwari; Adeel A Butt; Hamad Eid Al Romaihi; Mohamed H. Al-Thani; Abdullatif Al Khal; Roberto Bertollini.
Affiliation
  • Laith J Abu-Raddad; Weill Cornell Medicine-Qatar
  • Hiam Chemaitelly; Weill Cornell Medicine-Qatar
  • Houssein H. Ayoub; Qatar University
  • HADI M. YASSINE; Qatar University
  • Fatiha Benslimane; Qatar University
  • Hebah A. Al Khatib; Qatar University
  • Patrick Tang; Sidra Medicine
  • Mohammad Rubayet Hasan; Sidra Medicine
  • Peter Coyle; Hamad Medical Corporation
  • Sawsan AlMukdad; Weill Cornell Medicine-Qatar
  • Zaina Al Kanaani; Hamad Medical Corporation
  • Einas Al Kuwari; Hamad Medical Corporation
  • Andrew Jeremijenko; Hamad Medical Corporation
  • Anvar Hassan Kaleeckal; Hamad Medical Corporation
  • Ali Nizar Latif; Hamad Medical Corporation
  • Riyazuddin Mohammad Shaik; Hamad Medical Corporation
  • Hanan F. Abdul Rahim; Qatar University
  • Gheyath Nasrallah; Qatar University
  • Mohamed Ghaith Al Kuwari; Primary Health Care Corporation
  • Adeel A Butt; Hamad Medical Corporation
  • Hamad Eid Al Romaihi; Ministry of Public Health
  • Mohamed H. Al-Thani; Ministry of Public Health
  • Abdullatif Al Khal; Hamad Medical Corporation
  • Roberto Bertollini; Ministry of Public Health
Preprint in English | medRxiv | ID: ppmedrxiv-21261465
Journal article
A scientific journal published article is available and is probably based on this preprint. It has been identified through a machine matching algorithm, human confirmation is still pending.
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ABSTRACT
Severity (acute-care hospitalization), criticality (ICU hospitalization), and fatality of SARS-CoV-2 Beta (B.1.351) variant was investigated through case-control studies applied to complete national cohorts of infection, disease, and death cases in Qatar. Compared to Alpha (B.1.1.7) variant, odds of progressing to severe disease were 1.24-fold (95% CI 1.11-1.39) higher for Beta. Odds of progressing to critical disease were 1.49-fold (95% CI 1.13-1.97) higher. Odds of COVID-19 death were 1.57-fold (95% CI 1.03-2.43) higher. Findings highlight risks to healthcare systems, particularly to intensive care facilities and resources, with increased circulation of Beta.
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Full text: Available Collection: Preprints Database: medRxiv Type of study: Cohort_studies / Observational study / Prognostic study Language: English Year: 2021 Document type: Preprint
Full text: Available Collection: Preprints Database: medRxiv Type of study: Cohort_studies / Observational study / Prognostic study Language: English Year: 2021 Document type: Preprint
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