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SARS-CoV-2 Delta variant of concern in Brazil - multiple introductions, communitary transmission, and early signs of local evolution
Jose Patane; Vincent Viala; Loyze Lima; Antonio Martins; Claudia Barros; Elaine Marqueze; Jardelina Bernardino; Debora Moretti; Svetoslav Slavov; Rafael Bezerra; Evandra Rodrigues; Elaine Santos; Ricardo Brassaloti; Raquel Cassano; Pilar Mariani; Joao Kitajima; Bibiana Santos; Patricia Assato; Felipe Costa; Mirele Poleti; Jessika Lesbon; Elisangela Chicaroni; Cecilia Banho; Livia Sacchetto; Marilia Moraes; Melissa Palmieri; Fabiana Vilanova; Maiara Martininghi; Rejane Grotto; Jayme Souza-Neto; Marta Giovanetti; Luiz Alcantara; Mauricio Nogueira; Heidge Fukumasu; Luiz Coutinho; Rodrigo Calado; Simone Kashima; Raul Machado; Dimas Covas; Carolina Elias; Sandra Coccuzzo.
Affiliation
  • Jose Patane; Butantan Institute, Sao Paulo, Brazil
  • Vincent Viala; Butantan Institute, Sao Paulo, Brazil
  • Loyze Lima; Butantan Institute, Sao Paulo, Brazil
  • Antonio Martins; Butantan Institute, Sao Paulo, Brazil
  • Claudia Barros; Butantan Institute, Sao Paulo, Brazil
  • Elaine Marqueze; Butantan Institute, Sao Paulo, Brazil
  • Jardelina Bernardino; Butantan Institute, Sao Paulo, Brazil
  • Debora Moretti; Butantan Institute, Sao Paulo, Brazil
  • Svetoslav Slavov; University of Sao Paulo, Ribeirao Preto Medical School, Blood Center of Ribeirao Preto, Ribeirao Preto, SP, Brazil;
  • Rafael Bezerra; University of Sao Paulo, Ribeirao Preto Medical School, Blood Center of Ribeirao Preto, Ribeirao Preto, SP, Brazil;
  • Evandra Rodrigues; University of Sao Paulo, Ribeirao Preto Medical School, Blood Center of Ribeirao Preto, Ribeirao Preto, SP, Brazil;
  • Elaine Santos; University of Sao Paulo, Ribeirao Preto Medical School, Blood Center of Ribeirao Preto, Ribeirao Preto, SP, Brazil;
  • Ricardo Brassaloti; University of Sao Paulo, Centro de Genomica Funcional da ESALQ, Piracicaba, SP, Brazil
  • Raquel Cassano; University of Sao Paulo, Centro de Genomica Funcional da ESALQ, Piracicaba, SP, Brazil
  • Pilar Mariani; NGS Solucoes Genomicas, Piracicaba, SP, Brazil
  • Joao Kitajima; Mendelics Analise Genomica
  • Bibiana Santos; Mendelics Analise Genomica
  • Patricia Assato; Sao Paulo State University (UNESP), School of Agricultural Sciences, Department of Bioprocesses and Biotechnology, Botucatu, Brazil;
  • Felipe Costa; Sao Paulo State University (UNESP), School of Agricultural Sciences, Department of Bioprocesses and Biotechnology, Botucatu, Brazil;
  • Mirele Poleti; Department of Veterinary Medicine, School of Animal Science and Food Engineering, University of Sao Paulo, Pirassununga, Sao Paulo, Brazil;
  • Jessika Lesbon; Department of Veterinary Medicine, School of Animal Science and Food Engineering, University of Sao Paulo, Pirassununga, Sao Paulo, Brazil;
  • Elisangela Chicaroni; Department of Veterinary Medicine, School of Animal Science and Food Engineering, University of Sao Paulo, Pirassununga, Sao Paulo, Brazil;
  • Cecilia Banho; Medicine School of Sao Jose do Rio Preto (FAMERP), Sao Jose do Rio Preto, Sao Paulo, Brazil;
  • Livia Sacchetto; Medicine School of Sao Jose do Rio Preto (FAMERP), Sao Jose do Rio Preto, Sao Paulo, Brazil;
  • Marilia Moraes; Medicine School of Sao Jose do Rio Preto (FAMERP), Sao Jose do Rio Preto, Sao Paulo, Brazil;
  • Melissa Palmieri; Coordenacao de Vigilancia em Saude - Secretaria Municipal da Saude, Sao Paulo
  • Fabiana Vilanova; Assistencia Laboratorial/ Coordenacao de Atencao Basica - Secretaria Municipal da Saude, Sao Paulo
  • Maiara Martininghi; Coordenadoria de Vigilancia em Saude DVE/COVISA/SMS
  • Rejane Grotto; Sao Paulo State University (UNESP), School of Agricultural Sciences, Botucatu, Brazil; Molecular Biology Laboratory, Applied Biotechnology Laboratory, Clinical
  • Jayme Souza-Neto; Sao Paulo State University (UNESP), School of Agricultural Sciences, Botucatu, Brazil;
  • Marta Giovanetti; Instituto de Ciencias Biologicas, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil; Instituto Oswaldo Cruz, FIOCRUZ, Rio de Janeiro, B
  • Luiz Alcantara; Instituto de Ciencias Biologicas, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil; Instituto Oswaldo Cruz, FIOCRUZ, Rio de Janeiro, B
  • Mauricio Nogueira; Medicine School of Sao Jose do Rio Preto (FAMERP), Sao Jose do Rio Preto, Sao Paulo, Brazil;
  • Heidge Fukumasu; Department of Veterinary Medicine, School of Animal Science and Food Engineering, University of Sao Paulo, Pirassununga, Sao Paulo, Brazil;
  • Luiz Coutinho; University of Sao Paulo, Centro de Genomica Funcional da ESALQ, Piracicaba, SP, Brazil
  • Rodrigo Calado; University of Sao Paulo, Ribeirao Preto Medical School, Blood Center of Ribeirao Preto, Ribeirao Preto, SP, Brazil;
  • Simone Kashima; University of Sao Paulo, Ribeirao Preto Medical School, Blood Center of Ribeirao Preto, Ribeirao Preto, SP, Brazil;
  • Raul Machado; Butantan Institute, Sao Paulo, Brazil
  • Dimas Covas; University of Sao Paulo, Ribeirao Preto Medical School, Blood Center of Ribeirao Preto, Ribeirao Preto, SP, Brazil; Butantan Institute, Sao Paulo, Brazil
  • Carolina Elias; Butantan Institute, Sao Paulo, Brazil
  • Sandra Coccuzzo; Butantan Institute, Sao Paulo, Brazil
Preprint in English | medRxiv | ID: ppmedrxiv-21262846
ABSTRACT
The dissemination of the Delta VOC in Brazil is still unclear, despite the frequent reports of isolated cases from different Brazilian states. In this report we characterize the dissemination of the Delta VOC in Brazil and where the introductions of this lineage fall within the global Delta phylogeny. We also examined the mutational profile of the largest clade within the Brazilian Delta VOCs, with a focus on samples which were obtained in the State of Sao Paulo, and especially in the city of Sao Paulo, the largest metropolis of South America, and a national and international transportation hub.
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Full text: Available Collection: Preprints Database: medRxiv Language: English Year: 2021 Document type: Preprint
Fulltext
Add to My VHL
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Full text: Available Collection: Preprints Database: medRxiv Language: English Year: 2021 Document type: Preprint