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Monoclonal antibodies against SARS-CoV-2: potential game-changer still underused
Ivan Gentile; Alberto Enrico Maraolo; Antonio Riccardo Buonomo; Mariano Nobile; Prisco Piscitelli; Alessandro Miani; Nicola Schiano Moriello.
Affiliation
  • Ivan Gentile; Section of Infectious Diseases, Department of Clinical Medicine and Surgery, University of Naples Federico II, 80131 Naples, Italy
  • Alberto Enrico Maraolo; First Division of Infectious Diseases, Cotugno Hospital, AORN Dei Colli, 80131 Naples, Italy
  • Antonio Riccardo Buonomo; Section of Infectious Diseases, Department of Clinical Medicine and Surgery, University of Naples Federico II, 80131 Naples, Italy
  • Mariano Nobile; Section of Infectious Diseases, Department of Clinical Medicine and Surgery, University of Naples Federico II, 80131 Naples, Italy
  • Prisco Piscitelli; Euro Mediterranean Scientific Biomedical Institute, Bruxelles, Belgium
  • Alessandro Miani; Department of Environmental Science and Policy, University of Milan, Milan, Italy
  • Nicola Schiano Moriello; Section of Infectious Diseases, Department of Clinical Medicine and Surgery, University of Naples Federico II, 80131 Naples, Italy
Preprint in English | medRxiv | ID: ppmedrxiv-21264191
Journal article
A scientific journal published article is available and is probably based on this preprint. It has been identified through a machine matching algorithm, human confirmation is still pending.
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ABSTRACT
Even several months after the start of a massive vaccination campaign against COVID-19, mortality and hospital admission are still in considerable numbers in many nations. Monoclonal antibodies are the ideal complement to vaccination in high-risk subjects who have been infected by SARS-CoV-2 and are at high risk of developing severe disease. Combining data provided by clinal trials and demographics of SARS-CoV-2 infections, this analysis tries to predict the benefits of an extensive use of monoclonal antibodies to reduce hospital admissions, deaths, and costs.
License
cc_by_nc_nd
Full text: Available Collection: Preprints Database: medRxiv Type of study: Prognostic study Language: English Year: 2021 Document type: Preprint
Full text: Available Collection: Preprints Database: medRxiv Type of study: Prognostic study Language: English Year: 2021 Document type: Preprint
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