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Effectiveness of the neutralizing antibody sotrovimab among high-risk patients with mild to moderate SARS-CoV-2 in Qatar
Ahmed Zaqout; Muna A. Almaslamani; Hiam Chemaitelly; Samar A. Hashim; Ajithkumar Ittaman; Abeir Alimam; Fatma Rustom; Joanne Daghfal; Mohammed Abukhattab; Sawsan AlMukdad; Anvar Hassan Kaleeckal; Ali Nizar Latif; Adeel A Butt; Roberto Bertollini; Abdullatif Al-Khal; Ali S. Omrani; Laith J Abu-Raddad.
Affiliation
  • Ahmed Zaqout; Hamad Medical Corporation
  • Muna A. Almaslamani; Hamad Medical Corporation
  • Hiam Chemaitelly; Weill Cornell Medicine-Qatar
  • Samar A. Hashim; Hamad Medical Corporation
  • Ajithkumar Ittaman; Hamad Medical Corporation
  • Abeir Alimam; Hamad Medical Corporation
  • Fatma Rustom; Hamad Medical Corporation
  • Joanne Daghfal; Hamad Medical Corporation
  • Mohammed Abukhattab; Hamad Medical Corporation
  • Sawsan AlMukdad; Weill Cornell Medicine-Qatar
  • Anvar Hassan Kaleeckal; Hamad Medical Corporation
  • Ali Nizar Latif; Hamad Medical Corporation
  • Adeel A Butt; Hamad Medical Corporation
  • Roberto Bertollini; Ministry of Public Health
  • Abdullatif Al-Khal; Hamad Medical Corporation
  • Ali S. Omrani; Hamad Medical Corporation
  • Laith J Abu-Raddad; Weill Cornell Medicine-Qatar
Preprint in English | medRxiv | ID: ppmedrxiv-22274060
ABSTRACT
Effectiveness of sotrovimab against severe, critical, or fatal COVID-19 was investigated in Qatar using a case-control study design at a time when BA.2 Omicron subvariant dominated incidence. Adjusted odds ratio of progression to severe, critical, or fatal COVID-19, comparing those sotrovimab-treated to those untreated, was 2.67-fold higher (95% CI 0.60-11.91).
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Full text: Available Collection: Preprints Database: medRxiv Type of study: Experimental_studies / Observational study / Prognostic study Language: English Year: 2022 Document type: Preprint
Full text: Available Collection: Preprints Database: medRxiv Type of study: Experimental_studies / Observational study / Prognostic study Language: English Year: 2022 Document type: Preprint
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