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A study protocol for a retrospective cohort study and interrupted time series analysis to assess the effect of the COVID-19 pandemic on major trauma presentations and patient outcomes in English hospitals.
Carl Marincowitz; Omar Bouamra; Tim Coates; Dhushy Kumar; David Lockey; Lyndon Mason; Virgina Newcombe; Julian Thompson; David Yates; Fiona Lecky.
Affiliation
  • Carl Marincowitz; Centre for Urgent and Emergency Care Research (CURE), Health Services Research School of Health and Related Research, University of Sheffield, Regent Court, 30
  • Omar Bouamra; Trauma Audit Research Network, University of Manchester, Manchester, UK
  • Tim Coates; Emergency Medicine Academic Group, Department of Cardiovascular Sciences, University of Leicester, University Road, Leicester LE1 7RH, UK
  • Dhushy Kumar; Department of Critical Care, Anaesthesia and Pre-hospital Emergency Medicine, University Hospital Coventry, Coventry, UK
  • David Lockey; London Air Ambulance, Royal London Hospital, Whitechapel Road, London, E1 1BB, UK and North Bristol NHS Trust, Southmead Way, Bristol, BS10 5NB, UK
  • Lyndon Mason; Liverpool University Hospitals NHS Foundation Trust, University of Liverpool, Liverpool, UK
  • Virgina Newcombe; Division of Anaesthesia, University of Cambridge, Cambridge, UK
  • Julian Thompson; Department of Anaesthesia and Intensive Care Medicine, Southmead Hospital Intensive Care Unit, Southmead Hospital, North Bristol NHS Trust, Bristol, UK
  • David Yates; Trauma Audit Research Network, University of Manchester, Manchester, UK
  • Fiona Lecky; Centre for Urgent and Emergency Care Research (CURE), Health Services Research School of Health and Related Research, University of Sheffield, Regent Court, 30
Preprint in English | medRxiv | ID: ppmedrxiv-22274804
ABSTRACT
A protocol for a retrospective cohort study and interrupted time series analysis to investigate the effect of successive COVID related "lockdown" restrictions on major trauma presentations and patient outcomes in English hospitals. The study specifically aims to assess 1) The impact of successive "lockdowns" on the volume, demographics, injury mechanism, severity, treatment and outcomes of major trauma in England. 2) If the implementation of "lockdowns" affected major trauma related mortality. A patient cohort will be derived from the Trauma and Audit Research Network (TARN) database, for all trauma receiving hospitals in England, between 1st of January 2017 to 1st of September 2021. This period encompasses two national "lockdown" periods (23rd March 2020 to 29th June 2020 and 2nd Nov 2020 to 16th May 2021) in England. A time series will be used to illustrate changes in the volume and mechanism of injury associated with successive "lockdowns". Demographic characteristics and features of the clinical care pathways will be compared during the "lockdown" and equivalent pre-COVID periods. To specifically assess if there were any changes in risk adjusted mortality associated with the "lockdowns" interrupted time series analysis will be conducted.
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Full text: Available Collection: Preprints Database: medRxiv Type of study: Cohort_studies / Experimental_studies / Observational study / Prognostic study Language: English Year: 2022 Document type: Preprint
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Full text: Available Collection: Preprints Database: medRxiv Type of study: Cohort_studies / Experimental_studies / Observational study / Prognostic study Language: English Year: 2022 Document type: Preprint