Antidepressant-like effects of an apolar extract and chow enriched with Nepeta cataria (catnip) in mice
Psychol. neurosci. (Impr.)
; 3(2): 251-258, July-Dec. 2010. graf, tab
Article
in English
| Index Psychology - journals
| ID: psi-52260
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ABSTRACT
Nepeta cataria (catnip) is a plant used in pet toys and to treat human diseases. Catnip has also been used in the treatment of some depressive disorders. In this paper, we studied the antidepressant, anxiogenic, and motor activity effects of acute and repeated feeding of chow enriched with 10 percent N. cataria leaves and the acute and repeated administration of apolar and polar extracts of N. cataria leaves in male mice. The results showed that repeated feeding and acute and repeated administration with the apolar extract reduced immobility in the behavioral despair test but did not alter elevated plus maze and open-field parameters. Acute feeding and the acute and repeated administration of the polar extracts of N. cataria leaves did not alter the behavior of mice. These data suggest that N. cataria has antidepressant properties. Moreover, this antidepressant activity was present in the apolar extract.(AU)
Full text:
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Collection:
National databases
/
Brazil
Database:
Index Psychology - journals
Main subject:
Behavior, Animal
/
Motor Activity
/
Antidepressive Agents
Limits:
Animals
Language:
English
Journal:
Psychol. neurosci. (Impr.)
Year:
2010
Document type:
Article
/
Project document
Institution/Affiliation country:
Universidade Federal de São Paulo/Brazil
/
Universidade Presbiteriana Mackenzie/Brazil
/
Universidade de São Paulo/Brazil