Alternariol 9-methyl ether from the endophytic fungus Alternaria sp. Samif01 and its bioactivities
Braz. J. Microbiol.
; 47(1): 96-101, 2016. ilus, tab
Article
in En
| VETINDEX
| ID: vti-688324
Responsible library:
BR68.1
Localization: BR68.1
ABSTRACT
One bioactive compound, identified as alternariol 9-methyl ether, was isolated from the crude extract of the endophytic fungus Alternaria sp. Samif01 residing in the roots of Salvia miltiorrhiza Bunge. Alternariol 9-methyl ether was active against bacteria with minimum inhibitory concentration values ranging from 25 to 75 µg/mL and median inhibitory concentration (IC50) values ranging from 16.00 to 38.27 µg/mL. The IC50 value of alternariol 9-methyl ether against spore germination of Magnaporthe oryzae was 87.18 µg/mL. Alternariol 9-methyl ether also showed antinematodal activity against Bursaphelenchus xylophilus and Caenorhabditis elegans with IC50 values of 98.17 µg/mL and 74.62 µg/mL, respectively. This work is the first report on alternariol 9-methyl ether and its biological activities from the endophytic fungus Alternaria sp. Samif01 derived from S. miltiorrhiza Bunge. The results indicate the potential of Alternaria sp. Samif01 as a source of alternariol 9-methyl ether and also support that alternariol 9-methyl ether is a natural compound with high potential bioactivity against microorganisms. (AU)
Key words
Full text:
1
Database:
VETINDEX
Main subject:
Alternaria
/
Endophytes
/
Fungi
/
Methyl Ethers
Language:
En
Journal:
Braz. J. Microbiol.
Year:
2016
Document type:
Article