Comparative anthelminthic efficacy of nitroxynil, levamisole, closantel, moxidectin and fenbendazole on parasite control in sheep / Eficácia anti-helmíntica comparativa do nitroxinil, levamisol, closantel, moxidectina e fenbendazole no controle parasitário em ovinos
Bol. ind. anim. (Impr.)
; 74(1): 72-78, mar. 2017. tab
Article
in Pt
| VETINDEX
| ID: biblio-1466886
Responsible library:
BR68.1
Localization: BR68.1
ABSTRACT
The objective of this study was to evaluate the efficacy of different drugs in the control of parasites of sheep belonging to the Centro Agropecuário da Palma, Universidade Federal de Pelotas, municipality of Capão do Leão, RS. Seventy-eight female Corriedale and Ideal sheep with an initial body weight of 48.35 ± 4.71 kg were randomly selected and divided into six groups submitted to the following treatments control treatment and treated with 34%nitroxynil, 18.8% levamisole hydrochloride, 10% closantel, 1% moxidectin, and 10% fenbendazole. The drugs were administered according to the recommendations of the manufacturers. Fecal samples were collected before (day 0) and after treatment (days 7, 4, 21 and 28) and were used for the determination of fecal egg count (FEC) in the different groups. Efficacy was evaluated based on the percentage reduction in FEC and percent efficacy of the drugs. The fecal samples were processed for coproculture to identify the parasite genera present in the herd. The percentages of efficacy observed on day 28 post-treatment were 96.93% for nitroxynil, 95.8% for levamisole hydrochloride, 95.5% for closantel, 80.2% for moxidectin, and 27.5% for fenbendazole. The nematode species present in the herd was Haemonchus spp. (100%). Nitroxynil, closantel and levamisole hydrochloride are effective in eliminating gastrointestinal nematodes. There is anthelmintic resistance was observed to moxidectin and fenbendazole.
RESUMO
Objetivou-se avaliar a eficácia de diferentes fármacos no controle parasitário em ovinos do Centro Agropecuário da Palma, pertencente à Universidade Federal de Pelotas, localizado no município de Capão do Leão, RS. Foram utilizadas setenta e oito fêmeas das raças Corriedale e Ideal, com peso corporal inicial de 48,35 ± 4,71 kg, selecionadas aleatoriamente e distribuídas em seis grupos, um tratamento controle e os demais tratados com nitroxinil 34%, cloridrato de levamisol 18,8%, closantel 10%, moxidectina 1% e fenbendazole 10%. Os produtos foram administrados de acordo com as recomendações dos fabricantes. Amostras fecais foram coletadas no pré (dia 0) e no pós-tratamento (7º, 14º, 21º e 28º dias) e utilizadas para contagem de ovos por grama (OPG) nos distintos grupos. A eficácia foi avaliada através dos testes de percentual de redução de OPG e percentual de eficácia dos medicamentos. Amostras fecais foram submetidas à coprocultura para identificação dos gêneros de parasitos presentes no rebanho. Os percentuais de eficácia observados no 28º dia pós-tratamento foram 96,93% para o nitroxinil, 95,80% para o cloridrato de levamisol, 95,50% para o closantel, 80,20% para a moxidectina e 27,50% para o fenbendazole. Os nematódeos presentes no rebanho foram Haemonchus spp. (100%). Conclui-se que os princípios nitroxinil, closantel e cloridrato de levamisol são eficientes na eliminação de nematódeos gastrintestinais. Há resistência anti-helmíntica aos fármacos moxidectina e fenbendazole.
Key words
Full text:
1
Database:
VETINDEX
Main subject:
Sheep Diseases
/
Sheep
/
Levamisole
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Helminthiasis, Animal
/
Anthelmintics
/
Nitroxinil
Limits:
Animals
Language:
Pt
Journal:
B. Indústr. Anim.
/
Bol. ind. anim. (Impr.)
Year:
2017
Document type:
Article