Serum interleukins and urinary microglobulin in children with idiopathic nephrotic syndrome
(East. Mediterr. health j).
in English
| WHO IRIS
| ID: who-117031
Responsible library:
CH1.1
ABSTRACT
We studied 60 children affected with idiopathic nephrotic syndrome [INS] plus 20 age and sex matched controls. The children with INS were divided into 3 groups of 20 first presentation, remission and relapse. A complete blood picture and complete urinalysis were done. Serum interleukin [IL]-1beta, IL-6, tumour necrosis factor [TNF] and quantitative urinary beta-2-microglobulin [beta-2-m] excretion were estimated. IL-1beta and IL-6 were significantly higher in the study groups, the first presentation and relapse groups having the highest concentrations. Serum TNF concentration and urinary beta-2-m excretion were significantly higher in the first presentation and relapse groups. Serum IL-1beta, IL-6 and TNF concentrations were able to select positively [100%] the first presentation and relapse groups, while these plus urinary beta-2-m excretion selected negatively [100%] the control group
Full text:
Available
Collection:
Databases of international organizations
Database:
WHO IRIS
Main subject:
Blood Urea Nitrogen
/
Case-Control Studies
/
Chi-Square Distribution
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Child, Preschool
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Analysis of Variance
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Interleukin-1
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Hospitals, Pediatric
Language:
English
Journal:
East. Mediterr. health j
Year:
2005