T-cell cytokine production and endothelial dysfunction in type 2 diabetic patients with nephropathy
(East. Mediterr. health j).
in En
| WHOLIS
| ID: who-117702
Responsible library:
CH1.1
ABSTRACT
This study assessed changes in serum levels of cytokines IFNgamma and IL-10 [biomarkers of inflammatory changes] and soluble biomarkers sICAM-1 and sE-selectin [biomarkers of endothelial dysfunction] in diabetic patients with and without nephropathy. IFNgamma and IL-10 were significantly elevated in patients with diabetic nephropathy [DN] and end-stage renal disease [ESRD] compared with controls and diabetic patients without DN. IFNgamma and IL-10 levels were significantly increased after haemodialysis. sICAM-1 and sE-selectin were significantly higher in diabetic, DN and ESRD groups compared with controls, and sICAM-1 but not sE-selectin was increased after haemodialysis
Key words
Full text:
1
Collection:
04-international_org
Database:
WHOLIS
Main subject:
T-Lymphocytes
/
Renal Dialysis
/
Interferon-gamma
/
Interleukin-10
/
E-Selectin
/
Creatinine
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Diabetes Mellitus, Type 2
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Diabetic Nephropathies
/
Endothelium
Language:
En
Journal:
East. Mediterr. health j
Year:
2009