Total homocysteine levels and cardiovascular risk factors in healthy Tunisians
(East. Mediterr. health j).
in En
| WHOLIS
| ID: who-118225
Responsible library:
CH1.1
ABSTRACT
Hyperhomocysteinaemia is considered as an important independent risk factor for atherosclerosis and thrombotic disease. This study determined the distribution of homocysteine [Hcy] levels in healthy Tunisian subjects and evaluated the relationship between Hcy levels and some cardiovascular risk factors. Randomly selected subjects [592 men and 114 women] were recruited from different regions of Tunisia. The overall mean Hcy level was 12.6 [SD 5.4] micromol/L. Hcy levels in subjects with hyperhomocysteinaemia varied according to geographical region. Subjects with hyperhomocysteinaemia had significantly elevated total cholesterol, LDL cholesterol, apolipoprotein A and apolipoprotein B and lower vitamin B[12] levels compared with subjects with normohomocysteinaemia. Hey levels correlated with total cholesterol [r= 0.09], apolipoprotein A [r = 0.012], and B [r= 0.013] levels and total/HDL cholesterol ratio [r- =0.085]. Further epidemiological studies are needed to determine the precise role of Hcy in cardiovascular disease
Key words
Full text:
1
Collection:
04-international_org
Database:
WHOLIS
Main subject:
Cardiovascular Diseases
/
Surveys and Questionnaires
/
Risk Factors
/
Homocysteine
/
Lipids
Language:
En
Journal:
East. Mediterr. health j
Year:
2011