Clinical profile and factors associated with mortality in hospitalized patients with HIV/AIDS: a retrospective analysis from tripoli medical centre, Libya, 2013

ABSTRACT

In Libya, little is known about HIV-related hospitalizations and in-hospital mortality. This was a retrospective analysis of HIV-related hospitalizations at Tripoli Medical Centre in 2013. Of 227 cases analysed, 82.4% were males who were significantly older [40.0 versus 36.5 years], reported injection drug use [58.3% versus 0%] and were hepatitis C virus co-infected [65.8% versus 0%] compared with females. Severe immunosuppression was prevalent [median CD4 count = 42 cell/micro L]. Candidiasis was the most common diagnosis [26.0%]; Pneumocystis pneumonia was the most common respiratory disease [8.8%], while cerebral toxoplasmosis was diagnosed in 8.4% of patients.Current HAART use was independently associated with low risk of in-hospital mortality [OR 0.33], while central nervous system symptoms [OR 4.12], sepsis [OR 6.98]and low total lymphocyte counts [OR 3.60]were associated with increased risk.In this study, late presentation with severe immunosuppression was common, and was associated with significant in-hospital mortality