Possible Link between Serotonin and Interleukin 18 on Suicidality in Patients with Acute Coronary Syndrome
Clinical Psychopharmacology and Neuroscience
; : 386-390, 2023.
Article
in English
| WPRIM (Western Pacific)
| ID: wpr-1000115
Responsible library:
WPRO
ABSTRACT
Objective@#We investigated effects of serum serotonin and interleukin 18 levels on suicidal ideation (SI) at acute and chronic phases of acute coronary syndrome (ACS). @*Methods@#Recent-onset 969 ACS patients were evaluated for serum serotonin and interleukin 18 levels; and SI by the“suicidal thoughts” item of the Montgomery–Åsberg Depression Rating Scale. After 1-year, 711 patients were re-evaluated for SI. Logistic regression models were used adjustment for potential covariates. @*Results@#Associations between serum interleukin 18 and SI at both phases were significant only in the lower serotonin group. @*Conclusion@#By evaluating serum serotonin and interleukin 18 levels, the clinical prediction of SI of ACS may be improved.
Full text:
Available
Database:
WPRIM (Western Pacific)
Language:
English
Journal:
Clinical Psychopharmacology and Neuroscience
Year:
2023
Document type:
Article