Immune-mediated hemolysis after administration of human intravenous immunoglobulin in a dog: a case report
Korean Journal of Veterinary Research
; : e28-2023.
Article
in English
| WPRIM (Western Pacific)
| ID: wpr-1002468
Responsible library:
WPRO
ABSTRACT
A 10-year-old spayed female Maltese presented with purpura and hematemesis. Initial laboratory evaluation revealed immune-mediated thrombocytopenia, but evidence of hemolytic anemia was not identified. Three milligrams of human intravenous immunoglobulin (hIVIG) was administered for 3 hours following prednisolone and mycophenolate mofetil. A pale mucous membrane was identified, and the packed cell volume decreased by 3%. Blood film examination revealed significant spherocytosis with auto-agglutination. Blood transfusions and immunosuppression were continued for 4 days, and hIVIG was discontinued. This report describes a case of increased immune-mediated hemolysis after hIVIG administration, possibly due to new-onset immune-mediated hemolytic anemia or enhanced immunogenicity.
Full text:
Available
Database:
WPRIM (Western Pacific)
Language:
English
Journal:
Korean Journal of Veterinary Research
Year:
2023
Document type:
Article