Two Case Reports of Newly Diagnosed Crohn’s Disease after COVID-19 in Pediatric Patients / 대한소화기학회지
The Korean Journal of Gastroenterology
; : 163-167, 2023.
Article
in En
| WPRIM
| ID: wpr-1002921
Responsible library:
WPRO
ABSTRACT
Since the coronavirus disease 2019 (COVID-19) outbreak caused by the severe acute respiratory syndrome-coronavirus-2 virus (SARS-CoV-2), various complications have been reported. Although most COVID-19 cases exhibited flu-like symptoms, COVID-19 may dysregulate the immune response and promote overwhelming levels of inflammation in some patients. Inflammatory bowel disease (IBD) is caused by dysregulated or inappropriate immune responses to environmental factors in a genetically susceptible host, and a SARS-CoV-2 infection may act as a possible cause of IBD. This paper describes two pediatric patients who developed Crohn’s disease following a SARS-CoV-2 infection. They were previously healthy before the SARS-CoV-2 infection. On the other hand, they started to develop fever and gastrointestinal symptoms several weeks after recovery from the infection. They were diagnosed with Crohn’s disease by imaging and endoscopic studies, and their symptoms improved after treatment with steroids and azathioprine. This paper suggests that a SARS-CoV-2 infection may trigger IBD in predisposed patients.
Full text:
1
Database:
WPRIM
Language:
En
Journal:
The Korean Journal of Gastroenterology
Year:
2023
Document type:
Article