Secondary metabolites from Epicoccum nigrum 14one,an endophytic fungus isolated from plant Leptogium masiaticum / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 4021-4025, 2019.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-1008321
Responsible library:
WPRO
ABSTRACT
Phytochemical investigation of the culture of Epicoccum nigrum,an endolichenic fungus inhabiting Leptogium masiaticum,led to the isolation of 11 compounds. Based on NMR spectroscopy and HRESIMS data,their structures were determined as one alkaloid fusaricide( 1),and seven benzofuran derivatives including epicoccone( 2),4,6-dihydroxy-5-methoxy-7-methyl-1,3-dihydro isobenzofuran( 3),5-methyl-epicoccone B( 4),3,6,7-trihydroxy-5-methoxy-4-methylisobenzo furan-1( 3 H)-one( 5),3-methoxyepicoccone B( 6),2,3,4-trihydroxy-6-( hydroxymethyl)-5-methylbenzyl-alcohol( 7),and isoochracinic acid( 8),together with three epicoccolide analogs epicocconigrones A( 9),epicoccolide B( 10),and epicocconigrones B( 11). Compounds 1,9 and 10 showed potent microorganism inhibitory effects. These results indicated the potential perspective of this endophytic fungus as an eco-friendly biocide.
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Ascomycota
/
Magnetic Resonance Spectroscopy
/
Microbial Sensitivity Tests
/
Endophytes
/
Secondary Metabolism
Language:
Chinese
Journal:
China Journal of Chinese Materia Medica
Year:
2019
Document type:
Article