Irisin inhibits myocardial injury induced by cobalt dichloride through regulating Sirtl/UCP2 pathway / 中国药理学通报
Chinese Pharmacological Bulletin
; (12): 1061-1066, 2023.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-1013782
Responsible library:
WPRO
ABSTRACT
Aim To investigate the role and specific mechanisms of muscle factor Irisin in regulating the intracellular protective protein Sirtl and mitochondrial uncoupling protein 2 (UCP2) during myocardial hypoxia. Methods H9c2 cells were treated with CoC12 for 24 hours to construct an in vitro hypoxia model of myocardial cells. Six groups were divided in this experiment; control group (control), Irisin group (10 nmol • L
Full text:
Available
Database:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Pharmacological Bulletin
Year:
2023
Document type:
Article