Arctigenin attenuates airway inflammation in asthmatic mice via SIRT1/NLRP3 pathway

Yi-Hua PIAO; Yi-Hua PIAO; Yi-Lan SONG; Zhi-Guang WANG; Jing-Zhi JIANG; Liang-Chang LI; Hong-Mei PIAO; Guang-Hai YAN; Yi-Lan SONG; Jing-Zhi JIANG; Liang-Chang LI; Guang-Hai YAN; Zhi-Guang WANG; Hong-Mei PIAO

Arctigenin attenuates airway inflammation in asthmatic mice via SIRT1/NLRP3 pathway / 中国药理学通报

Yi-Hua PIAO; Yi-Hua PIAO; Yi-Lan SONG; Zhi-Guang WANG; Jing-Zhi JIANG; Liang-Chang LI; Hong-Mei PIAO; Guang-Hai YAN; Yi-Lan SONG; Jing-Zhi JIANG; Liang-Chang LI; Guang-Hai YAN; Zhi-Guang WANG; Hong-Mei PIAO.

Chinese Pharmacological Bulletin ; (12): 498-504, 2021.

Article in Chinese | WPRIM (Western Pacific) | ID: wpr-1014389

Responsible library: WPRO

ABSTRACT

ABSTRACT

Aim To investigate the efficacy of arctigenin on airway inflammation in a mouse model of asthma and the mechanism related to the SIRT1/NLRP3 signaling pathway. Methods Forty female BALB/c mice of clean grade were selected and divided into control group, OVA model group and ATG group (5, 10 and 20 mg · kg

airway inflammation; arctigenin; asthma; cytokine; NLRP3; SIRT1

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Full text: Available Database: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Pharmacological Bulletin Year: 2021 Document type: Article

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Full text: Available Database: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Pharmacological Bulletin Year: 2021 Document type: Article