Cyclovirobuxine D ameliorates aldosterone-induced primary neonatal rat cardiac myocyte injury via Ca

Guang-Qiong ZHANG; Sheng-Quan WANG; Ling-Yun FU; Yi-Ni XU; Hong LUO; Ling TAO; Xiang-Chun SHEN; Ling LI; Guang-Qiong ZHANG; Sheng-Quan WANG; Ling-Yun FU; Yi-Ni XU; Hong LUO; Ling TAO; Xiang-Chun SHEN; Ling LI

Cyclovirobuxine D ameliorates aldosterone-induced primary neonatal rat cardiac myocyte injury via Ca / 中国药理学通报

Guang-Qiong ZHANG; Sheng-Quan WANG; Ling-Yun FU; Yi-Ni XU; Hong LUO; Ling TAO; Xiang-Chun SHEN; Ling LI; Guang-Qiong ZHANG; Sheng-Quan WANG; Ling-Yun FU; Yi-Ni XU; Hong LUO; Ling TAO; Xiang-Chun SHEN; Ling LI.

Chinese Pharmacological Bulletin ; (12): 564-570, 2021.

Article in Zh | WPRIM | ID: wpr-1014399

Responsible library: WPRO

ABSTRACT

ABSTRACT

Aim To investigate the protective effect of cyclovirobuxine D(CVB-D) on aldosterone (ALD)-induced primary neonatal rat cardiac myocytes (PNRC-Ms) injury and the possible mechanism. Methods PNRCMs were extracted by trypsin, and the PNRCMs injury model was established by ALD (10 μmol · L

Key words

aldosterone; apoptosis; calcium ion; CaMK II; cyclovirobuxine D; myocardial cell injury

Fulltext

Add to My VHL

XML

Search on Google

Full text: 1 Database: WPRIM Language: Zh Journal: Chinese Pharmacological Bulletin Year: 2021 Document type: Article

Fulltext

Add to My VHL

XML

Search on Google

Full text: 1 Database: WPRIM Language: Zh Journal: Chinese Pharmacological Bulletin Year: 2021 Document type: Article