Advances on protective effects of gypenosides on neural disorders and underlying mechanisms / 中国药理学通报

ABSTRACT

Gypenosides (GP), the main medicinal ingredient of Gynostemma Pentaphyllum Makino, exhibits excellent protective effect on various neural diseases through several mechanisms, including anti-inflammation, anti-oxidative stress and pro-neural regeneration. In the current review, we have made a summary on the research progress of GP on neural disorders, like Alzheimer' s disease, Parkinson' s disease, depression, hypoxic brain injury and so on, aiming to provide an experimental basis for the further research and drug development of GP.