Hederagenin improves psoriasis skin lesions by inhibiting macrophage mincle-mediated inflammation / 中国临床药理学与治疗学
Chinese Journal of Clinical Pharmacology and Therapeutics
; (12): 1339-1346, 2023.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-1014585
Responsible library:
WPRO
ABSTRACT
AIM:
To observe the effects and mechanisms of hederagenin (HDG) in improving psoriasis skin lesions and inflammation in mice.METHODS:
A mouse model of psoriasis was established by depilation of the back and continuous application of imiquimod for 7 days in C57 mice. After modeling, HDG was administered orally (low dose 25 mg · kg
Full text:
Available
Database:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Clinical Pharmacology and Therapeutics
Year:
2023
Document type:
Article