Progress of Research on Glucagon-like Peptide-2 in Gastrointestinal Tract / 胃肠病学
Chinese Journal of Gastroenterology
; (12): 563-567, 2022.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-1016091
Responsible library:
WPRO
ABSTRACT
Glucagon⁃like peptide⁃2 (GLP⁃2) is a peptide hormone secreted by L cells in the gut. GLP⁃2 plays an important role in anti⁃inflammation, promoting proliferation and repair, and promoting nutrient absorption through various signaling pathways in the gastrointestinal tract. Long ⁃ acting analogs of GLP ⁃ 2 have been used in the treatment of short bowel syndrome and Crohn’s disease, but using GLP⁃2 also has the risk of promoting tumorigenesis. This article introduces GLP ⁃ 2 and its physiological role in gastrointestinal tract, and expounds the possible mechanism of GLP ⁃ 2 related to tumorigenesis and the tumorigenesis risk of endogenous and exogenous GLP⁃2 therapy.
Full text:
Available
Database:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Gastroenterology
Year:
2022
Document type:
Article