Histopathological and immunohistochemical findings of primary and metastatic medullary thyroid carcinoma in a young dog
Journal of Veterinary Science
; : 449-453, 2014.
Article
in En
| WPRIM
| ID: wpr-106729
Responsible library:
WPRO
ABSTRACT
This report describes the gross, histological, and immunohistochemical features of medullary thyroid carcinoma (MTC) with pulmonary metastases in a young dog. Sheets of pleomorphic cells supported by fibrous stroma characterized the primary mass, while metastatic nodules had a neuroendocrine pattern. Despite differing histologic features, all masses showed marked immunoreactivity against calcitonin and multiple neuroendocrine markers consistent with MTC. Although MTC is a well-recognized entity, it may be difficult to distinguish this mass from other thyroid neoplasms, necessitating immunohistochemical characterization.
Key words
Full text:
1
Database:
WPRIM
Main subject:
Thyroid Neoplasms
/
Laryngeal Neoplasms
/
Carcinoma, Neuroendocrine
/
Dog Diseases
/
Lung Neoplasms
/
Neoplasm Metastasis
Type of study:
Diagnostic_studies
Limits:
Animals
Language:
En
Journal:
Journal of Veterinary Science
Year:
2014
Document type:
Article