Comparison of clinical outcomes between ABO-compatible and ABO-incompatible spousal donor kidney transplantation
Kidney Research and Clinical Practice
; : 50-54, 2016.
Article
in English
| WPRIM (Western Pacific)
| ID: wpr-110776
Responsible library:
WPRO
ABSTRACT
BACKGROUND:
Kidney transplantation (KT) is the treatment of choice for end-stage renal disease patients. The spouse is a major donor in living KT. Clinical outcomes of spousal donor KT are not inferior to those of living related donor KT. In this study, we compared clinical outcomes between ABO-compatible (ABOc) and ABO-incompatible (ABOi) spousal donor KTs.METHODS:
Thirty-two cases of spousal donor KT performed from January 2011 to August 2013 were analyzed retrospectively. Twenty-one ABOc KTs and 11 ABOi KTs were performed. We investigated patient survival, graft survival, acute rejection, graft function, and complications.RESULTS:
During follow-up, patient and graft survival rates were 100% in both groups. There were no significant differences in the incidence of delayed graft function, acute rejection, and the change in graft function between the 2 groups. Medical and surgical complications were not significantly different between the groups.CONCLUSION:
The clinical outcomes of ABOc and ABOi spousal donor KTs were equivalent. In ABOi KT, an emotionally motivated spousal donor KT may be a good alternative to the problem of the absolute shortage of kidney donations.
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Tissue Donors
/
Blood Group Incompatibility
/
Incidence
/
Retrospective Studies
/
Follow-Up Studies
/
Kidney Transplantation
/
Spouses
/
Transplants
/
Delayed Graft Function
/
Graft Rejection
Type of study:
Incidence study
/
Observational study
/
Prognostic study
/
Risk factors
Limits:
Humans
Language:
English
Journal:
Kidney Research and Clinical Practice
Year:
2016
Document type:
Article