Balanced approach can help initial outcomes: analysis of initial 50 cases of a new liver transplantation program in East Asia
Annals of Surgical Treatment and Research
; : 22-27, 2014.
Article
in English
| WPRIM (Western Pacific)
| ID: wpr-112287
Responsible library:
WPRO
ABSTRACT
PURPOSE:
To evaluate patient triage pattern and outcomes according to types of liver transplantation as part of a new liver transplant program developed in an East Asian country with a limited number of deceased donors.METHODS:
Medical records of initial 50 liver transplantations were reviewed retrospectively.RESULTS:
Twenty-nine patients underwent deceased donor liver transplantation (DDLT) and 21 patients underwent living donor liver transplantation (LDLT). Mean model for end-stage liver disease scores of recipients of DDLT and LDLT were 24.9 +/- 11.6 and 13.1 +/- 5.4, respectively (P < 0.0001). Twenty-eight patients had HCCs and 17 of them (60.7%) underwent LDLT, which was 80.9% of LDLTs. There were 2 cases of perioperative mortality; each was from DDLT and LDLT, respectively. Median follow-up was 18 months. Overall patient and graft survival rates at 6 months, 1 and 2 years were 95.7%, 93.4%, and 89.8%, respectively. There was no significant difference in survival between DDLT and LDLT. Overall recurrence-free survival rates of hepatocellular carcinoma (HCC) patients at 6 month, 1, and 2 years were 96.3%, 96.3%, and 90.3%, respectively. There was no significant difference in recurrence-free survival between DDLT and LDLT.CONCLUSION:
As a new liver transplant program with limited resource and waiting list, patients with critical condition could undergo DDLT whereas relatively stable patients with HCCs were mostly directed to LDLT. We recommend a balanced approach between DDLT and LDLT for initiating liver transplant programs.
Full text:
Available
Health context:
SDG3 - Target 3.4 Reduce premature mortality due to noncommunicable diseases
Health problem:
Digestive System Diseases
/
Liver Cancer
Database:
WPRIM (Western Pacific)
Main subject:
Tissue Donors
/
Medical Records
/
Survival Rate
/
Retrospective Studies
/
Follow-Up Studies
/
Mortality
/
Triage
/
Waiting Lists
/
Liver Transplantation
/
Carcinoma, Hepatocellular
Type of study:
Observational study
/
Prognostic study
Limits:
Humans
Country/Region as subject:
Asia
Language:
English
Journal:
Annals of Surgical Treatment and Research
Year:
2014
Document type:
Article