Effects of Percutaneous Coronary Intervention on Depressive Symptoms in Chronic Stable Angina Patients
Psychiatry Investigation
; : 252-256, 2012.
Article
in En
| WPRIM
| ID: wpr-119422
Responsible library:
WPRO
ABSTRACT
OBJECTIVE: Depression is present in 1 of 5 outpatients with coronary artery disease (CAD), and a well-documented risk factor for recurrent cardiac events and mortality. We examined the impact of percutaneous coronary intervention (PCI), on depressive symptoms, in chronic stable angina (CSA) patients. METHODS: On prospective and non-randomized trial, consecutive CSA patients (n=171), who had undergone coronary angiography from January 2006 to December 2007, were included. Patients were subdivided into PCI and non-PCI groups, and then completed 21-item the Beck Depression Inventory II (BDI-II), at the baseline and pre-discharge, to assess the depressive symptoms. RESULTS: A total of 108 (63%) patients were assigned to the non-PCI group, and 63 (37%) patients to the PCI group. Using an independent t-test, we found that patients with PCI were significantly older (non-PCI vs. PCI; 57+/-11 vs. 64+/-10, years, p<0.001), had more joint disease (12.0 vs. 27.0%, p=0.013), more stroke history (5.6 vs. 17.5%, p=0.012) and higher incident of family history of cardiovascular disease (28.7 vs. 46.0%, p=0.025), but less religion (54.6 vs. 36.5%, p=0.002) and private health insurance (43.5 vs. 20.6%, p=0.002). The mean difference of BDI-II score between the baseline and pre-discharge was higher in patients with PCI (OR: 1.266; 95% CI: 1.146-1.398, p<0.001). CONCLUSION: In conclusion, PCI contributes independently to higher risk of developing depressive symptoms in CSA patients during hospitalization; Routine assessment and management of PCI related depressive symptoms are justified.
Key words
Full text:
1
Database:
WPRIM
Main subject:
Outpatients
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Coronary Artery Disease
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Cardiovascular Diseases
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Prospective Studies
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Risk Factors
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Coronary Angiography
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Angioplasty
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Stroke
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Depression
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Angina, Stable
Type of study:
Clinical_trials
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Diagnostic_studies
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Etiology_studies
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Observational_studies
/
Risk_factors_studies
Limits:
Humans
Language:
En
Journal:
Psychiatry Investigation
Year:
2012
Document type:
Article