EDTA-dependent Pseudothrombocytopenia Confirmed by Supplementation of Kanamycin: A Case Report
The Korean Journal of Internal Medicine
; : 65-68, 2002.
Article
in En
| WPRIM
| ID: wpr-123524
Responsible library:
WPRO
ABSTRACT
EDTA-dependent pseudothrombocytopenia (PTCP) is the phenomenon of a spurious low platelet count due to EDTA-induced aggregation of platelets. Since the failure to recognize EDTA-dependent PTCP may result in incorrect diagnosis and inappropriate treatment, the recognition of this phenomenon is very important. We report an insidious case of EDTA-dependent PTCP confirmed by supplementation of kanamycin to anticoagulant in a 53-year-old women. Although sodium citrate and heparin usually prevented the aggregation of platelets in EDTA-dependent PTCP patients, these anticoagulants failed in preventing PTCP in our case. EDTA-dependent PTCP was confirmed by the findings that the clumping of platelets on microscopic evaluation was found in EDTA-anticoagulated blood samples, whereas thrombocytopenia and platelet aggregation were not revealed in the sample supplemented with kanamycin.
Key words
Full text:
1
Database:
WPRIM
Main subject:
Platelet Count
/
Thrombocytopenia
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Platelet Aggregation Inhibitors
/
Kanamycin
/
Platelet Aggregation
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Edetic Acid
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Middle Aged
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Anti-Bacterial Agents
/
Anticoagulants
Limits:
Female
/
Humans
Language:
En
Journal:
The Korean Journal of Internal Medicine
Year:
2002
Document type:
Article