Frequency of Silent Myocardial Ischemia Detected by Thallium-201 SPECT in Patients with Type 2 Diabetes / 당뇨병
Korean Diabetes Journal
; : 225-231, 2009.
Article
in Korean
| WPRIM (Western Pacific)
| ID: wpr-124697
Responsible library:
WPRO
ABSTRACT
BACKGROUND:
Silent myocardial ischemia (SMI) is more common in diabetic patients than among the general population. It is not yet established whether a routine screening test for SMI is necessary, and which screening test would be most useful. The purpose of this study was to estimate the prevalence of SMI detected by Thallium-201 perfusion single photon emission computed tomography (SPECT) in type 2 diabetic patients.METHODS:
A total of 173 asymptomatic type 2 diabetic patients were included in the study. Thallium-201 perfusion SPECT was performed to screen for SMI.RESULTS:
Among the 173 patients, abnormal perfusion patterns were found in 11 patients. Coronary angiography was carried out for these patients, and significant coronary artery stenosis was found in ten of them (positive predictive value; 90.9%). There was a significant association between SMI and overt albuminuria (OR = 7.33, 95% CI, 1.825-29.437).CONCLUSION:
Thallium-201 perfusion SPECT is not sensitive enough to identify SMI, but is accurate in detecting decreased myocardial perfusion. This may be a useful screening tool for detecting SMI in type 2 diabetic patients with impaired renal function.
Full text:
Available
Health context:
SDG3 - Health and Well-Being
Health problem:
Target 3.4: Reduce premature mortality due to noncommunicable diseases
Database:
WPRIM (Western Pacific)
Main subject:
Perfusion
/
Tomography, Emission-Computed, Single-Photon
/
Mass Screening
/
Prevalence
/
Coronary Angiography
/
Myocardial Ischemia
/
Coronary Stenosis
/
Diabetes Mellitus, Type 2
/
Albuminuria
Type of study:
Prevalence study
/
Screening study
Limits:
Humans
Language:
Korean
Journal:
Korean Diabetes Journal
Year:
2009
Document type:
Article