Safety of umbilical cord milking in very preterm neonates: a randomized controlled study
Obstetrics & Gynecology Science
; : 527-534, 2017.
Article
in English
| WPRIM (Western Pacific)
| ID: wpr-126357
Responsible library:
WPRO
ABSTRACT
OBJECTIVE:
To investigate the safety of umbilical cord milking on both the mother and neonate among very preterm deliveries of less than 33 weeks of gestation.METHODS:
Pregnant women who were expected to deliver at between 24 0/7 and 32 6/7 weeks of gestation were randomized to either the umbilical cord milking or immediate cord clamping group. Maternal and neonatal data associated with delivery, in addition to neonatal morbidity and mortality data, were collected and analyzed.RESULTS:
Of the 66 preterm deliveries included in the study, 34 were randomized into the milking and 32 into the clamping group. Differences between maternal pre- and post-partum hemoglobin levels were 1.35 g/dL in the milking and 1.58 g/dL in the clamping group (P=0.451). Neonatal Apgar scores at both 1 and 5 minutes, initial blood gas analysis results, body temperature at admission, need for early intubation, and maximum bilirubin levels were all similar between the 2 groups. However, neonatal hemoglobin levels at birth (15.79 vs. 14.69 g/dL; P<0.05) and at 24 hours of age (14.83 vs. 13.29 g/dL; P<0.05) were significantly higher in the milking group. Neonates in the clamping group required more blood transfusion (1.78 vs. 0.93; P=0.049), and a higher percentage of neonates in the clamping group required inotropic drugs (63% vs. 29%; P=0.007). The mortality rate was significantly lower in the milking group (6% vs. 28%; P=0.015).CONCLUSION:
Umbilical cord milking can be a safe and beneficial procedure for both the mother and the neonate in deliveries of less than 33 weeks of gestation.
Full text:
Available
Health context:
SDG3 - Health and Well-Being
/
SDG3 - Target 3.2 Reduce avoidable death in newborns and children under 5
Health problem:
Target 3.1: Reduce maternal mortality
/
Target 3.2: Reduce avoidable death in newborns and children under 5
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Neonatal Healthcare
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Noncommunicable Diseases
Database:
WPRIM (Western Pacific)
Main subject:
Umbilical Cord
/
Bilirubin
/
Blood Gas Analysis
/
Blood Transfusion
/
Body Temperature
/
Infant, Premature
/
Mortality
/
Constriction
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Parturition
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Pregnant Women
Type of study:
Controlled clinical trial
/
Prognostic study
Limits:
Female
/
Humans
/
Infant, Newborn
/
Pregnancy
Language:
English
Journal:
Obstetrics & Gynecology Science
Year:
2017
Document type:
Article