The Adjacent Vessel Sign on Breast MRI: New Data and a Subgroup Analysis for 1,084 Histologically Verified Cases
Korean Journal of Radiology
; : 178-186, 2010.
Article
in English
| WPRIM (Western Pacific)
| ID: wpr-127079
Responsible library:
WPRO
ABSTRACT
OBJECTIVE:
The adjacent vessel sign (AVS) is a descriptor for differentiating malignant from benign breast lesions on breast MRI (bMRI). This investigation was designed to verify the previous reports on the diagnostic accuracy of AVS and to assess correlation between AVS, histopathological diagnosis, lesion size and lesion grade. MATERIALS ANDMETHODS:
This study was approved by the local ethical committee. Experienced radiologists evaluated 1,084 lesions. The exclusion criteria were no histological verification after bMRI and breast interventions that were done up to one year before bMRI (surgery, core biopsy, chemo- or radiation therapy). The native and dynamic contrast-enhanced T1-weighted series were acquired using standardized protocols. The AVS was rated positive if a vessel leading to a lesion could be visualized. Prevalence of an AVS was correlated with the lesions' size, grade and histology using Chi-square-tests.RESULTS:
The AVS was significantly associated with malignancy (p 2 cm more often presented with an AVS than did those malignant lesions < 2 cm (p < 0.0001; sensitivity 65%, PPV 90%). There was no correlation of the AVS with the tumor grade. The prevalence of an AVS didn't significantly differ between invasive lobular carcinomas versus ductal carcinomas. In situ cancers were less frequently associated with an AVS (p < 0.001).CONCLUSION:
The adjacent vessel sign was significantly associated with malignancy. Thus, it can be used to accurately assess breast lesions on bMRI. In this study, the AVS was particularly associated with advanced and invasive carcinomas.
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Breast
/
Breast Neoplasms
/
Magnetic Resonance Imaging
/
Image Enhancement
/
Observer Variation
/
Predictive Value of Tests
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Reproducibility of Results
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Sensitivity and Specificity
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Neoplasms, Ductal, Lobular, and Medullary
/
Contrast Media
Type of study:
Diagnostic study
/
Practice guideline
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Prognostic study
Aspects:
Ethical aspects
Limits:
Adolescent
/
Adult
/
Aged
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Aged, 80 and over
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Female
/
Humans
Language:
English
Journal:
Korean Journal of Radiology
Year:
2010
Document type:
Article