Pneumatosis Intestinalis Developed due to CMV Infection in a Pediatric Severe Aplastic Anemia Patient after Hematopoietic Stem Cell Transplantation / 임상소아혈액종양
Clinical Pediatric Hematology-Oncology
; : 112-115, 2013.
Article
in Korean
| WPRIM (Western Pacific)
| ID: wpr-130763
Responsible library:
WPRO
ABSTRACT
A 10-year old girl diagnosed as severe aplastic anemia was transplanted with peripheral stem cells from a CMV seropositive full matched unrelated donor. The conditioning regimen consisted of busulfan, fludarabine, and anti-thymocyte globulin (ATG). At D+114, abdominal pain, fever, and blood-tinged watery diarrhea developed. At D+116, pneumatosis intestinalis (PI) was detected on simple abdominal X-ray and computed tomography (CT). Ganciclovir was started intravenously because CMV antigenemia was detected at D+117. Two days later, PI sign disappeared on simple abdominal X-ray, and hematochezia began to decrease. CMV antigenemia disappeared 10 days after starting ganciclovir. We describe a 10-year old girl with severe aplastic anemia who developed PI in the presence of CMV infection and gastro-intestinal graft-versus-host-disease (GVHD) after allogeneic stem cell transplantation and was treated successfully with ganciclovir.
Full text:
Available
Health context:
SDG3 - Health and Well-Being
/
Neglected Diseases
Health problem:
Target 3.3: End transmission of communicable diseases
/
Diarrhea
/
Neglected Diseases
Database:
WPRIM (Western Pacific)
Main subject:
Stem Cells
/
Vidarabine
/
Busulfan
/
Hematopoietic Stem Cells
/
Abdominal Pain
/
Ganciclovir
/
Hematopoietic Stem Cell Transplantation
/
Stem Cell Transplantation
/
Diarrhea
/
Fever
Limits:
Female
/
Humans
Language:
Korean
Journal:
Clinical Pediatric Hematology-Oncology
Year:
2013
Document type:
Article