The Effect of Hormonal Replacement Therapy on Breast
Journal of the Korean Radiological Society
; : 457-463, 1995.
Article
in Korean
| WPRIM (Western Pacific)
| ID: wpr-13218
Responsible library:
WPRO
ABSTRACT
PURPOSE:
To evaluate mammographic and sonographic breast parenchymal changes and the risk of breast cancer in women on hormonal replacement therapy (HRT). MATERIAL ANDMETHODS:
The study group consisted of 50 patients examined with serial mammograms and/or ultrasonograms during HRT. The control group consisted of 50 patients examined with serial mammogram for a routine health check. Mammographic parenchymal changes in both the study and control groups and so- nographic findings of 27/50 patients in study group were evaluated.RESULTS:
Follow-up mammogram of the control group showed no interval change or slight evolution of parenchyma with increasing age, but the study group showed increasing parenchymal densities. Most frequently encountered finding on SOhogram in 11 women treated by estrogen alone, was ductal dilatation (7cases ;64%), whereas in 16 women treated by estrogen and progesteron it was ductal epithelial hyperplasia (8 cases; 50%). Overall, four breast cancers developed;one infiltrating ductal carcinoma and three ductal carcinoma in situ.CONCLUSION:
HRT causes the changes of breast parenchyma on mammogram and sonogram of postmenopausal women, and increases the risk of developing breast cancer. Therefore, careful and regular examination should be followed in those on postmenopausal HRT.
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Breast
/
Breast Neoplasms
/
Follow-Up Studies
/
Ultrasonography
/
Carcinoma, Intraductal, Noninfiltrating
/
Carcinoma, Ductal
/
Dilatation
/
Estrogens
/
Hyperplasia
Type of study:
Diagnostic study
/
Observational study
/
Prognostic study
Limits:
Female
/
Humans
Language:
Korean
Journal:
Journal of the Korean Radiological Society
Year:
1995
Document type:
Article