A case of acute interstitial nephritis associated with cimetidine therapy / 대한내과학회지
Korean Journal of Medicine
; : 941-945, 1999.
Article
in Korean
| WPRIM (Western Pacific)
| ID: wpr-139230
Responsible library:
WPRO
ABSTRACT
Although cimetidine causes a transient rise in serum creatinine without reduction of renal function, acute renal failure due to acute interstitial nephritis is rare in patients after cimetidine treatment. We here present a case of acute renal failure and acute interstitial nephritis that occurred during cimetidine treatment. A 38-year old woman was referred to our hospital because of nausea and general weakness. She had been taking cimetidine for 3 weeks because of epigasric discomfort. On admission, serum creatinine was 3.9 mg/dL and urinalysis showed mild proteinuria and hematuria. There was no history of pyelonephritis, diabetes mellitus, hypertension, toxin exposure. Renal biopsy showed severe interstitial infiltration of lymphocytes without definite glomerular change. After withdrawal of cimetidine, renal function completely recovered.
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Proteinuria
/
Pyelonephritis
/
Biopsy
/
Lymphocytes
/
Cimetidine
/
Urinalysis
/
Creatinine
/
Diabetes Mellitus
/
Acute Kidney Injury
/
Hematuria
Limits:
Adult
/
Female
/
Humans
Language:
Korean
Journal:
Korean Journal of Medicine
Year:
1999
Document type:
Article